Are Noonan syndrome and Noonan-like/multiple giant cell lesion syndrome distinct entities?

2001 ◽  
Vol 98 (3) ◽  
pp. 230-234 ◽  
Author(s):  
D�bora R. Bertola ◽  
Chong A. Kim ◽  
Alexandre C. Pereira ◽  
Gl�ria F.A. Mota ◽  
Jos� E. Krieger ◽  
...  
Keyword(s):  
Giant Cell ◽  
Noonan Syndrome ◽  
Giant Cell Lesion

scholarly journals A novel PTPN11 gene mutation bridges Noonan syndrome, multiple lentigines/LEOPARD syndrome and Noonan-like/multiple giant cell lesion syndrome

2004 ◽  
Vol 12 (12) ◽  
pp. 1069-1072 ◽  
Author(s):  
Anna Sarkozy ◽  
Maria Gabriela Obregon ◽  
Emanuela Conti ◽  
Giorgia Esposito ◽  
Rita Mingarelli ◽  
...  
Keyword(s):  
Giant Cell ◽  
Gene Mutation ◽  
Noonan Syndrome ◽  
Leopard Syndrome ◽  
Ptpn11 Gene ◽  
Giant Cell Lesion ◽  
Multiple Lentigines

scholarly journals Unilateral giant cell lesion of the jaw in Noonan syndrome

2014 ◽  
Vol 97 (2) ◽  
pp. 90 ◽  
Author(s):  
M Eyselbergs ◽  
F Vanhoenacker ◽  
J Hintjens ◽  
M Dom ◽  
K Devriendt ◽  
...  
Keyword(s):  
Giant Cell ◽  
Noonan Syndrome ◽  
Giant Cell Lesion

scholarly journals Central giant cell lesion of the mandible in a 2-year old girl

2017 ◽  
Vol 47 (3) ◽  
pp. 209 ◽  
Author(s):  
Takaaki Oda ◽  
Mikiko Sue ◽  
Yasuo Okada ◽  
Yoriaki Kanri ◽  
Junya Ono ◽  
...  
Keyword(s):  
Giant Cell ◽  
Giant Cell Lesion ◽  
Central Giant Cell Lesion

PERIPHERAL GIANT CELL LESION: CASE REPORT

2017 ◽  
Vol 124 (2) ◽  
pp. e116
Author(s):  
FABIANA DE FREITAS BOMBARDA NUNES ◽  
ZILDA FAGUNDES OLIVEIRA ◽  
RENATO RODRIGUES MARANO ◽  
FERNANDA MOMBRINI PIGATTI ◽  
LILIANA APARECIDA PIMENTA DE BARROS ◽  
...  
Keyword(s):  
Case Report ◽  
Giant Cell ◽  
Giant Cell Lesion

Aggressive Central Giant Cell Lesion of Maxilla: a Case Report

2018 ◽  
Vol 126 (3) ◽  
pp. e100
Author(s):  
Nara Rúbia Pereira De Siqueira ◽  
Diego Antônio Arantes ◽  
Vanessa Milani ◽  
Maria Alves Garcia Santos Silva ◽  
Elismauro Francisco De Mendonça ◽  
...  
Keyword(s):  
Case Report ◽  
Giant Cell ◽  
Giant Cell Lesion ◽  
Central Giant Cell Lesion

scholarly journals Central giant cell lesions with an unusual behavior in patient with Noonan syndrome: A case report with 8-year follow-up

2021 ◽  
Vol 10 (1) ◽  
pp. e13510111563
Author(s):  
Gleysson Matias de Assis ◽  
Marcelo Leite Machado da Silveira ◽  
José Wittor de Macêdo Santos ◽  
Humberto Pereira Chaves Neto ◽  
Lucas Melo da Costa ◽  
...  
Keyword(s):  
Giant Cell ◽  
Noonan Syndrome ◽  
Pulmonary Stenosis ◽  
Clinical Information ◽  
Patient Discharge ◽  
Blood Analysis ◽  
Unusual Behavior ◽  
Ptpn11 Gene ◽  
Mandibular Injuries

This study describes a patient with Noonan syndrome affected by multiple Central Giant Cell Lesions (CGCL) in jaws. The lesions presented an unusual behavior since there was no regression size after puberty. The syndrome was diagnosed by collecting clinical information, represented by ocular hypertelorism, low insertion of ears, pulmonary stenosis, cryptorchidism, cardiac abnormalities, short stature, multiple CGCL in the jaws, and blood analysis that found a mutation of the PTPN11 gene. The treatment consisted of systemic calcitonin for a period of 14 months and three surgical procedures at distinct moments. The patient is currently with 20 years and in the eighth-year of follow-up. Although he presented an improvement in deformity, radiological findings showed remodeling without resolution of mandibular injuries, making it clear that injuries will did not always regress after puberty and not confirm previously publications in the literature. We therefore advocate a larger time of follow-up before patient discharge in these cases.

An Extensive Mandibular Central Giant Cell Lesion in a 15-Year-Old Girl

2018 ◽  
Vol 126 (3) ◽  
pp. e108
Author(s):  
Mayana Júlia Cunha Santos ◽  
Gabriel Sousa E Silva ◽  
Mariana Araújo Dos Santos ◽  
Kamilla Guedes Silva ◽  
Ana Cláudia Garcia Rosa ◽  
...  
Keyword(s):  
Giant Cell ◽  
Giant Cell Lesion ◽  
Central Giant Cell Lesion
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